TUMOR-RELATED METHYLATED CELL-FREE DNA AND CIRCULATING TUMOR CELLS IN MELANOMA

Solid tumor release into the circulation cell-free DNA (cfDNA) and circulating tumor cells (CTCs) which represent promising biomarkers for cancer diagnosis. Circulating tumor DNA may be studied in plasma from cancer patients by detecting tumor specific alterations, such as genetic or epigenetic modi...

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Bibliographic Details
Main Authors: Francesca eSalvianti, Claudio eOrlando, Daniela eMassi, Vincenzo eDe Giorgi, Marta eGrazzini, Mario ePazzagli, Pamela ePinzani
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-01-01
Series:Frontiers in Molecular Biosciences
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmolb.2015.00076/full