Bacterial Cyclodipeptides Target Signal Pathways Involved in Malignant Melanoma

Bacterial Cyclodipeptides Target Signal Pathways Involved in Malignant Melanoma

Melanoma is an aggressive cancer that utilizes multiple signaling pathways, including those that involve oncogenes, proto-oncogenes, and tumor suppressors. It has been suggested that melanoma formation requires cross-talk of the PI3K/Akt/mTOR and Ras-ERK pathways. This pathway cross-talk has been as...

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Bibliographic Details
Main Authors: Mayra Xóchitl Durán-Maldonado, Laura Hernández-Padilla, Juan Carlos Gallardo-Pérez, Alma Laura Díaz-Pérez, Lorena Martínez-Alcantar, Homero Reyes De la Cruz, José Salud Rodríguez-Zavala, Gustavo Pacheco-Rodríguez, Joel Moss, Jesús Campos-García
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Oncology
Subjects:
antitumor activity
cyclodipeptides
tumorigenesis
melanoma
cell proliferation
apoptosis
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2020.01111/full

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https://www.frontiersin.org/article/10.3389/fonc.2020.01111/full

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