Treatment of terminal peritoneal carcinomatosis by a transducible p53-activating peptide.

Advanced-stage peritoneal carcinomatosis is resistant to current chemotherapy treatment and, in the case of metastatic ovarian cancer, results in a devastating 15%-20% survival rate. Therapeutics that restore genes inactivated during oncogenesis are predicted to be more potent and specific than curr...

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Bibliographic Details
Main Authors: Eric L Snyder, Bryan R Meade, Cheryl C Saenz, Steven F Dowdy
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2004-02-01
Series:PLoS Biology
Online Access:http://europepmc.org/articles/PMC340944?pdf=render