Computation of Robust Minimal Intervention Sets in Multi-Valued Biological Regulatory Networks

Computation of Robust Minimal Intervention Sets in Multi-Valued Biological Regulatory Networks

Enabled by rapid advances in computational sciences, in silico logical modeling of complex and large biological networks is more and more feasible making it an increasingly popular approach among biologists. Automated high-throughput, drug target identification is one of the primary goals of this in...

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Bibliographic Details
Main Authors: Hooman Sedghamiz, Matthew Morris, Darrell Whitley, Travis J. A. Craddock, Michael Pichichero, Gordon Broderick
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-03-01
Series:Frontiers in Physiology
Subjects:
target identification
logical modeling
algorithms
signaling networks
experimental design
drug therapy
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2019.00241/full

Internet

https://www.frontiersin.org/article/10.3389/fphys.2019.00241/full

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