Establishment of induced pluripotent stem cells from a patient with 16p13.11 duplication and VPS13B deletion

VPS13B deletion and 16p13.11 duplication are related to mental disorders, such as schizophrenia. However, how these variants affect human neurons and contribute to the development of mental disorders is yet to be elucidated. In this study, we generated induced pluripotent stem cells (iPSCs) from a p...

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Bibliographic Details
Main Authors: Hiroki Okumura, Yuko Arioka, Itaru Kushima, Daisuke Mori, Norio Ozaki
Format: Article
Language:English
Published: Elsevier 2022-10-01
Series:Stem Cell Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506122002331