Multifunctional AIE iridium (III) photosensitizer nanoparticles for two-photon-activated imaging and mitochondria targeting photodynamic therapy

Multifunctional AIE iridium (III) photosensitizer nanoparticles for two-photon-activated imaging and mitochondria targeting photodynamic therapy

Abstract Developing novel photosensitizers for deep tissue imaging and efficient photodynamic therapy (PDT) remains a challenge because of the poor water solubility, low reactive oxygen species (ROS) generation efficiency, serve dark cytotoxicity, and weak absorption in the NIR region of conventiona...

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Bibliographic Details
Main Authors: Xuzi Cai, Kang-Nan Wang, Wen Ma, Yuanyuan Yang, Gui Chen, Huijiao Fu, Chunhui Cui, Zhiqiang Yu, Xuefeng Wang
Format: Article
Language:English
Published: BMC 2021-08-01
Series:Journal of Nanobiotechnology
Subjects:
Cyclometalated iridium nanoparticles
Two-photon excitation
Mitochondria-targeted
Fluorescence imaging
Photodynamic therapy
Online Access:https://doi.org/10.1186/s12951-021-01001-4

Internet

https://doi.org/10.1186/s12951-021-01001-4

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