Hypothalamic Nesfatin-1 Resistance May Underlie the Development of Type 2 Diabetes Mellitus in Maternally Undernourished Non-obese Rats

Hypothalamic Nesfatin-1 Resistance May Underlie the Development of Type 2 Diabetes Mellitus in Maternally Undernourished Non-obese Rats

Intrauterine growth retardation (IUGR) poses a high risk for developing late-onset, non-obese type 2 diabetes (T2DM). The exact mechanism underlying this phenomenon is unknown, although the contribution of the central nervous system is recognized. The main hypothalamic nuclei involved in the homeost...

Full description

Bibliographic Details
Main Authors: Máté Durst, Katalin Könczöl, Klementina Ocskay, Klaudia Sípos, Péter Várnai, Anett Szilvásy-Szabó, Csaba Fekete, Zsuzsanna E. Tóth
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-03-01
Series:Frontiers in Neuroscience
Subjects:
IP-ITT
IP-GTT
neuronal birth dating
cFos
arcuate nucleus
nesfatin-1
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2022.828571/full

Internet

https://www.frontiersin.org/articles/10.3389/fnins.2022.828571/full

Similar Items