Integrated metabolomics, network pharmacology and biological verification to reveal the mechanisms of Nauclea officinalis treatment of LPS-induced acute lung injury

Integrated metabolomics, network pharmacology and biological verification to reveal the mechanisms of Nauclea officinalis treatment of LPS-induced acute lung injury

Abstract Background Acute lung injury (ALI) is a severe inflammatory disease, underscoring the urgent need for novel treatments. Nauclea officinalis Pierre ex Pitard (Danmu in Chinese, DM) is effective in treating inflammatory respiratory diseases. However, there is still no evidence of its protecti...

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Bibliographic Details
Main Authors: Han Xu, Sicong Xu, Liyan Li, Yuhuang Wu, Shiying Mai, Yiqiang Xie, Yinfeng Tan, Ailing Li, Fengming Xue, Xiaoning He, Yonghui Li
Format: Article
Language:English
Published: BMC 2022-11-01
Series:Chinese Medicine
Subjects:
Acute lung injury
Nauclea officinalis
Metabolomics
Network pharmacology
Mechanisms
Online Access:https://doi.org/10.1186/s13020-022-00685-6

Internet

https://doi.org/10.1186/s13020-022-00685-6

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