Pharmaceutical development of tablets containing a spray-dried optimized extract from Lippia origanoides H. B. K.: influence of excipients and toxicological assessment

Pharmaceutical development of tablets containing a spray-dried optimized extract from Lippia origanoides H. B. K.: influence of excipients and toxicological assessment

ABSTRACT Lippia origanoides is a honey shrub which has showed hypotensive potential assessed by in vivo studies. The aim of this work is the development of a pharmaceutical formulation composed by an optimized extract obtained from aerial parts of L. origanoides. The quantification of the naringenin...

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Bibliographic Details
Main Authors: Angélica Gomes Coelho, José de Sousa Lima Neto, Arkellau Kenned Silva Moura, Ilmara Cecilia Pinheiro da Silva Morais, Francisco Valmor Macedo Cunha, Bernardo Melo-Neto, Maria das Graças Freire de Medeiros, Eilika Andreia Feitosa Vasconcelos, Daniel Dias Rufino Arcanjo, Lívio Cesar Cunha Nunes, Antônia Maria das Graças Lopes Citó
Format: Article
Language:English
Published: Universidade de São Paulo 2018-07-01
Series:Brazilian Journal of Pharmaceutical Sciences
Subjects:
Lippia origanoides/pharmaceutical formulation/toxicity/
Babassu mesocarp
Factorial planning
Tablets.
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502018000200619&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502018000200619&lng=en&tlng=en

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