TNNI3K is a novel mediator of myofilament function and phosphorylates cardiac troponin I

The phosphorylation of cardiac troponin I (cTnI) plays an important role in the contractile dysfunction associated with heart failure. Human cardiac troponin I-interacting kinase (TNNI3K) is a novel cardiac-specific functional kinase that can bind to cTnI in a yeast two-hybrid screen....

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Bibliographic Details
Main Authors: Hui Wang, Lin Wang, Li Song, Yan-Wan Zhang, Jue Ye, Rui-Xia Xu, Na Shi, Xian-Min Meng
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2013-02-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2013000200128&lng=en&tlng=en