Engineering CAR T cells for enhanced efficacy and safety
Despite its success in treating hematologic malignancies, chimeric antigen receptor (CAR) T cell therapy faces two major challenges which hinder its broader applications: the limited effectiveness against solid tumors and the nonspecific toxicities. To address these concerns, researchers have used s...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
AIP Publishing LLC
2022-03-01
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Series: | APL Bioengineering |
Online Access: | http://dx.doi.org/10.1063/5.0073746 |