Engineering CAR T cells for enhanced efficacy and safety

Engineering CAR T cells for enhanced efficacy and safety

Despite its success in treating hematologic malignancies, chimeric antigen receptor (CAR) T cell therapy faces two major challenges which hinder its broader applications: the limited effectiveness against solid tumors and the nonspecific toxicities. To address these concerns, researchers have used s...

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Bibliographic Details
Main Authors:	Yiqian Wu, Ziliang Huang, Reed Harrison, Longwei Liu, Linshan Zhu, Yinglin Situ, Yingxiao Wang
Format:	Article
Language:	English
Published:	AIP Publishing LLC 2022-03-01
Series:	APL Bioengineering
Online Access:	http://dx.doi.org/10.1063/5.0073746

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