FARP‐1 deletion is associated with lack of response to autism treatment by early start denver model in a multiplex family

FARP‐1 deletion is associated with lack of response to autism treatment by early start denver model in a multiplex family

Abstract Background Children with autism spectrum disorder (ASD) display impressive clinical heterogeneity, also involving treatment response. Genetic variants can contribute to explain this large interindividual phenotypic variability. Methods Array‐CGH (a‐CGH) and whole genome sequencing (WGS) wer...

Full description

Bibliographic Details
Main Authors: Francesca Cucinotta, Arianna Ricciardello, Laura Turriziani, Giorgia Calabrese, Marilena Briguglio, Maria Boncoddo, Fabiana Bellomo, Pasquale Tomaiuolo, Silvia Martines, Marianna Bruschetta, Francesca La Fauci Belponer, Tiziana Di Bella, Costanza Colombi, Marco Baccarin, Chiara Picinelli, Paola Castronovo, Carla Lintas, Roberto Sacco, Thomas Biederer, Barbara Kellam, Stephen W. Scherer, Antonio M. Persico
Format: Article
Language:English
Published: Wiley 2020-09-01
Series:Molecular Genetics & Genomic Medicine
Subjects:
autism spectrum disorder
biomarkers
FARP1
neuronal plasticity
treatment outcome
Online Access:https://doi.org/10.1002/mgg3.1373

Internet

https://doi.org/10.1002/mgg3.1373

Similar Items