Gene Expression Signature in Adipose Tissue of Acromegaly Patients.

To study the effect of chronic excess growth hormone on adipose tissue, we performed RNA sequencing in adipose tissue biopsies from patients with acromegaly (n = 7) or non-functioning pituitary adenomas (n = 11). The patients underwent clinical and metabolic profiling including assessment of HOMA-IR...

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Detalhes bibliográficos
Principais autores: Irit Hochberg, Quynh T Tran, Ariel L Barkan, Alan R Saltiel, William F Chandler, Dave Bridges
Formato: Artigo
Idioma:English
Publicado em: Public Library of Science (PLoS) 2015-01-01
coleção:PLoS ONE
Acesso em linha:http://europepmc.org/articles/PMC4472931?pdf=render