Cellular reprogramming to model and study epigenetic alterations in cancer
Although genetic mutations are required for cancer development, reversible non-genetic alterations also play a pivotal role in cancer progression. Failure of well-orchestrated gene regulation by chromatin states and master transcription factors can be one such non-genetic etiology for cancer develop...
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Format: | Article |
Language: | English |
Published: |
Elsevier
2020-12-01
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Series: | Stem Cell Research |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1873506120303639 |