The introduction of an N-glycosylation site into prochymosin greatly enhances its production and secretion by Pichia pastoris

The introduction of an N-glycosylation site into prochymosin greatly enhances its production and secretion by Pichia pastoris

Abstract Background N-glycosylation is one of the most important post-translational modifications. Many studies have shown that N-glycosylation has a significant effect on the secretion level of heterologous glycoproteins in yeast cells. However, there have been few studies reporting a clear and uni...

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Bibliographic Details
Main Authors: Nan Wang, Caifeng Yang, Huakang Peng, Wenfang Guo, Mengqi Wang, Gangqiang Li, Dehu Liu
Format: Article
Language:English
Published: BMC 2022-08-01
Series:Microbial Cell Factories
Subjects:
N-glycosylation
Prochymosin
Secretion
Pichia pastoris
Differential interacting proteins
Online Access:https://doi.org/10.1186/s12934-022-01904-3

Internet

https://doi.org/10.1186/s12934-022-01904-3

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