Glucose Activates Lysine-Specific Demethylase 1 through the KEAP1/p62 Pathway

Glucose Activates Lysine-Specific Demethylase 1 through the KEAP1/p62 Pathway

Endometrial cancer incidence increases annually. Several risk factors, including high glucose intake, are associated with endometrial cancer. We investigated whether glucose affects lysine-specific demethylase 1 (LSD1) expression and the responsible molecular mechanisms. A high concentration of gluc...

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Bibliographic Details
Main Authors: Chiao-Yun Lin, Chen-Bin Chang, Ren-Chin Wu, Angel Chao, Yun-Shien Lee, Chi-Neu Tsai, Chih-Hao Chen, Chih-Feng Yen, Chia-Lung Tsai
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Antioxidants
Subjects:
p62
KEAP1
LSD1
NRF2
endometrial cells
Online Access:https://www.mdpi.com/2076-3921/10/12/1898

Internet

https://www.mdpi.com/2076-3921/10/12/1898

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