Baseline host determinants of robust human HIV-1 vaccine-induced immune responses: A meta-analysis of 26 vaccine regimens

Baseline host determinants of robust human HIV-1 vaccine-induced immune responses: A meta-analysis of 26 vaccine regimens

Summary: Background: The identification of baseline host determinants that associate with robust HIV-1 vaccine-induced immune responses could aid HIV-1 vaccine development. We aimed to assess both the collective and relative performance of baseline characteristics in classifying individual particip...

Full description

Bibliographic Details
Main Authors: Yunda Huang, Yuanyuan Zhang, Kelly E. Seaton, Stephen De Rosa, Jack Heptinstall, Lindsay N. Carpp, April Kaur Randhawa, Lyle R. McKinnon, Paul McLaren, Edna Viegas, Glenda E. Gray, Gavin Churchyard, Susan P. Buchbinder, Srilatha Edupuganti, Linda-Gail Bekker, Michael C. Keefer, Mina C. Hosseinipour, Paul A. Goepfert, Kristen W. Cohen, Brian D. Williamson, M. Juliana McElrath, Georgia D. Tomaras, Juilee Thakar, James J. Kobie
Format: Article
Language:English
Published: Elsevier 2022-10-01
Series:EBioMedicine
Subjects:
Baseline characteristics
SuperLearner
Variable importance measurements
Vaccine response heterogeneity
Antibody
CD4+ T cell
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396422004534

Internet

http://www.sciencedirect.com/science/article/pii/S2352396422004534

Similar Items