Association between decreased klotho blood levels and organic growth hormone deficiency in children with growth impairment.

Klotho is an aging-modulating protein expressed mainly in the kidneys and choroid plexus, which can also be shed, released into the circulation and act as a hormone. Klotho deficient mice are smaller compared to their wild-type counterparts and their somatotropes show marked atrophy and reduced numb...

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Main Authors: Ido Wolf, Shiri Shahmoon, Michal Ben Ami, Yael Levy-Shraga, Kineret Mazor-Aronovitch, Orit Pinhas-Hamiel, Yonatan Yeshayahu, Rina Hemi, Hannah Kanety, Tami Rubinek, Dalit Modan-Moses
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4157849?pdf=render