Investigation of spleen CXCR4 expression by [68Ga]Pentixafor PET in a cohort of 145 solid cancer patients

Investigation of spleen CXCR4 expression by [68Ga]Pentixafor PET in a cohort of 145 solid cancer patients

Abstract Background The chemokine receptor CXCR4 is frequently overexpressed and associated with adverse prognosis in most hematopoietic malignancies and solid cancers. Recently, CXCR4 molecular imaging using the CXCR4-specific positron emission tomography (PET) tracer Pentixafor ([68Ga]Pentixafor)...

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Bibliographic Details
Main Authors: Richard Lewis, Stefan Habringer, Malte Kircher, Maike Hefter, Caroline Anna Peuker, Rudolf Werner, Valëza Ademaj-Kospiri, Alexander Gäble, Wolfgang Weber, Hans-Jürgen Wester, Andreas Buck, Peter Herhaus, Constantin Lapa, Ulrich Keller
Format: Article
Language:English
Published: SpringerOpen 2021-08-01
Series:EJNMMI Research
Subjects:
Solid tumors
Clinical studies
Retrospective studies
Molecular imaging
PET
CXCR4
Online Access:https://doi.org/10.1186/s13550-021-00822-6

Internet

https://doi.org/10.1186/s13550-021-00822-6

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