Non-Invasive Quantification of Cartilage Using a Novel In Vivo Bioluminescent Reporter Mouse.

Mouse models are common tools for examining post-traumatic osteoarthritis (OA), which involves cartilage deterioration following injury or stress. One challenge to current mouse models is longitudinal monitoring of the cartilage deterioration in vivo in the same mouse during an experiment. The objec...

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Bibliographic Details
Main Authors: Sarah E Mailhiot, Donald L Zignego, Justin R Prigge, Ella R Wardwell, Edward E Schmidt, Ronald K June
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4495059?pdf=render