Diazoxide and Exercise Enhance Muscle Contraction during Obesity by Decreasing ROS Levels, Lipid Peroxidation, and Improving Glutathione Redox Status

Obesity causes insulin resistance and hyperinsulinemia which causes skeletal muscle dysfunction resulting in a decrease in contraction force and a reduced capacity to avoid fatigue, which overall, causes an increase in oxidative stress. K<sub>ATP</sub> channel openers such as diazoxide a...

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Bibliographic Details
Main Authors: Mariana Gómez-Barroso, Koré M. Moreno-Calderón, Elizabeth Sánchez-Duarte, Christian Cortés-Rojo, Alfredo Saavedra-Molina, Alain R. Rodríguez-Orozco, Rocío Montoya-Pérez
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Antioxidants
Subjects:
Online Access:https://www.mdpi.com/2076-3921/9/12/1232