Prenatal Zinc Supplementation Ameliorates Hippocampal Astrocytes Activation and Inflammatory Cytokines Expression Induced by Lipopolysaccharide in a Rat Model of Maternal Immune Activation

Prenatal Zinc Supplementation Ameliorates Hippocampal Astrocytes Activation and Inflammatory Cytokines Expression Induced by Lipopolysaccharide in a Rat Model of Maternal Immune Activation

Introduction: Evidence suggests that gestational exposure to Lipopolysaccharide (LPS) results in fetal zinc deficiency and eventually neurodevelopmental abnormalities. In this study, we utilized a rat model of Maternal Immune Activation (MIA) to investigate the possible neuroprotective effects of zi...

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Bibliographic Details
Main Authors: Ebrahim Savareh, Nahid Davoodian, Ronak Mousaviyan, Maryam Ghasemi-Kasman, Ali Atashabparvar, Ebrahim Eftekhar
Format: Article
Language:English
Published: Iran University of Medical Sciences 2022-05-01
Series:Basic and Clinical Neuroscience
Subjects:
maternal immune activation
maternal zinc supplementation
schizophrenia
lipopolysaccharide
hippocampus
inflammatory markers
Online Access:http://bcn.iums.ac.ir/article-1-2153-en.html

Internet

http://bcn.iums.ac.ir/article-1-2153-en.html

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