The role of osteopontin (OPN/SPP1) haplotypes in the susceptibility to Crohn's disease.

The role of osteopontin (OPN/SPP1) haplotypes in the susceptibility to Crohn's disease.

BACKGROUND: Osteopontin represents a multifunctional molecule playing a pivotal role in chronic inflammatory and autoimmune diseases. Its expression is increased in inflammatory bowel disease (IBD). The aim of our study was to analyze the association of osteopontin (OPN/SPP1) gene variants in a larg...

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Main Authors: Jürgen Glas, Julia Seiderer, Corinna Bayrle, Martin Wetzke, Christoph Fries, Cornelia Tillack, Torsten Olszak, Florian Beigel, Christian Steib, Matthias Friedrich, Julia Diegelmann, Darina Czamara, Stephan Brand
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3248444?pdf=render

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http://europepmc.org/articles/PMC3248444?pdf=render

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