Rationally designed approaches to augment CAR-T therapy for solid tumor treatment

Rationally designed approaches to augment CAR-T therapy for solid tumor treatment

Chimeric antigen receptor T cell denoted as CAR-T therapy has realized incredible therapeutic advancements for B cell malignancy treatment. However, its therapeutic validity has yet to be successfully achieved in solid tumors. Different from hematological cancers, solid tumors are characterized by d...

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Bibliographic Details
Main Authors: Chaojie Zhu, Qing Wu, Tao Sheng, Jiaqi Shi, Xinyuan Shen, Jicheng Yu, Yang Du, Jie Sun, Tingxizi Liang, Kaixin He, Yuan Ding, Hongjun Li, Zhen Gu, Weilin Wang
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2024-03-01
Series:Bioactive Materials
Subjects:
CAR-T therapy
Cancer immunotherapy
Drug delivery
CAR construct design
Tumor modulation
Delivery strategy
Online Access:http://www.sciencedirect.com/science/article/pii/S2452199X23003511

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http://www.sciencedirect.com/science/article/pii/S2452199X23003511

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