Facile construction of irinotecan loaded mesoporous nano-formulation with surface-initiated polymerization to improve stimuli-responsive drug delivery for breast cancer therapy

Facile construction of irinotecan loaded mesoporous nano-formulation with surface-initiated polymerization to improve stimuli-responsive drug delivery for breast cancer therapy

This work uses rice husk to fabricate mesoporous silica nanoparticles (D-RMN) for breast cancer therapy. The biocompatible dual-responsive (DAN-RMN) was developed by polymerizing acrylic acid (AA) and n-isopropyl acrylamide (NIPAM) on the DV-RMN surface monomeric ratio to increase drug delivery effi...

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Bibliographic Details
Main Authors: Zheng Nie, Daoliang Wang, Shuangyan Wang, Linling Wang
Format: Article
Language:English
Published: Elsevier 2023-04-01
Series:Heliyon
Subjects:
Irinotecan
Nanotherapy
Mesoporous silica
Breast cancer
Apoptosis
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844023022946

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http://www.sciencedirect.com/science/article/pii/S2405844023022946

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