Lack of chitin synthase genes impacts capsular architecture and cellular physiology in Cryptococcus neoformans

Cryptococcus neoformans mutants lacking each of the eight putative chitin synthase genes (CHS) have been previously generated. However, it is still unclear how deletion of chitin synthase genes affects the cryptococcal capsule. Since the connections between chitin metabolism and capsular polysacchar...

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Bibliographic Details
Main Authors: Jessica Rodrigues, Caroline L. Ramos, Susana Frases, Rodrigo M. da C. Godinho, Fernanda L. Fonseca, Marcio L. Rodrigues
Format: Article
Language:English
Published: Elsevier 2018-06-01
Series:The Cell Surface
Online Access:http://www.sciencedirect.com/science/article/pii/S2468233018300057