Enhancing immune protection against MERS-CoV: the synergistic effect of proteolytic cleavage sites and the fusion peptide and RBD domain targeting VLP immunization

Enhancing immune protection against MERS-CoV: the synergistic effect of proteolytic cleavage sites and the fusion peptide and RBD domain targeting VLP immunization

IntroductionThe Middle East Respiratory Syndrome Coronavirus (MERS-CoV) is a zoonotic infectious virus that has caused significant outbreaks in the Middle East and beyond. Due to a highly mortality rate, easy transmission, and rapid spread of the MERS-CoV, it remains as a significant public health t...

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Bibliographic Details
Main Authors: Jeein Oh, Uni Park, Juhyung Kim, Kyeongseok Jeon, Chulwoo Kim, Nam-Hyuk Cho, Youn Soo Choi
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-05-01
Series:Frontiers in Immunology
Subjects:
MERS-CoV
PSFP
RBD
virus-like particle (VLP) immunization
spike specific IgG
immune protection
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1201136/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1201136/full

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