Cross-Protection against Acute <i>Staphylococcus aureus</i> Lung Infection in Mice by a D-Glutamate Auxotrophic Vaccine Candidate

Cross-Protection against Acute <i>Staphylococcus aureus</i> Lung Infection in Mice by a D-Glutamate Auxotrophic Vaccine Candidate

<i>Staphylococcus aureus</i> is regarded as a threatening bacterial pathogen causing invasive pneumonia in healthcare settings and in the community. The continuous emergence of multidrug resistant strains is narrowing the treatment options for these infections. The development of an effe...

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Bibliographic Details
Main Authors: Patricia García, Maria P. Cabral, Alejandro Beceiro, Miriam Moscoso, Germán Bou
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Vaccines
Subjects:
live-attenuated vaccine
<i>Staphylococcus aureus</i>
auxotrophic
intranasal immunization
glutamate racemase gene
D-amino acid transaminase gene
Online Access:https://www.mdpi.com/2076-393X/11/2/210

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https://www.mdpi.com/2076-393X/11/2/210

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