PTB and TIAR binding to insulin mRNA 3′- and 5′UTRs; implications for insulin biosynthesis and messenger stability

Objectives: Insulin expression is highly controlled on the posttranscriptional level. The RNA binding proteins (RBPs) responsible for this result are still largely unknown. Methods and results: To identify RBPs that bind to insulin mRNA we performed mass spectrometry analysis on proteins that bound...

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Bibliographic Details
Main Authors: Rikard G. Fred, Syrina Mehrabi, Christopher M. Adams, Nils Welsh
Format: Article
Language:English
Published: Elsevier 2016-09-01
Series:Heliyon
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844016301797