Multiple Sclerosis between genetics and infections: Human Endogenous Retroviruses in monocytes and macrophages.

The aetiology of Multiple Sclerosis is still unknown, but there is strong evidence that genetic predisposition associated with environmental factors can trigger the disease. An estimated 30 million years ago, exogenous retroviruses are thought to have integrated themselves into human germ line cells...

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Bibliographic Details
Main Authors: Elena eMorandi, Rachael E Tarlinton, Bruno eGran
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-12-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2015.00647/full