Novel Eudragit® -based polymeric nanoparticles for sustained release of simvastatin

Novel Eudragit® -based polymeric nanoparticles for sustained release of simvastatin

This paper reports on the development of nanoparticles aiming at the in vitro controlled release of simvastatin (SVT). The nanoparticles were prepared by the nanoprecipitation method with polymers Eudragit® FS30D (EDGFS) or Eudragit® NE30D (EDGNE). EDGFS+SVT nanoparticles showed mean size of 148.8 n...

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Bibliographic Details
Main Authors: Deborah Fernandes Rodrigues, Renê Oliveira do Couto, Rubén Dario Sinisterra, Carlos Eduardo de Matos Jensen
Format: Article
Language:English
Published: Universidade de São Paulo 2020-11-01
Series:Brazilian Journal of Pharmaceutical Sciences
Subjects:
Simvastatin
Nanoparticles
Poly-methylmethacrylate
Dissolution
Drug delivery systems
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502020000100591&tlng=en

Internet

http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502020000100591&tlng=en

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