Differentiation roadmap of embryonic Sertoli cells derived from mouse embryonic stem cells

Differentiation roadmap of embryonic Sertoli cells derived from mouse embryonic stem cells

Abstract Background Embryonic Sertoli cells (eSCs) play an important role in sex determination and in male gonad development which makes them a very useful cell type for therapeutic applications. However, the deriving mechanism of Sertoli cells has been unclear and challenging to create a large numb...

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Bibliographic Details
Main Authors: Chenze Xu, Ali Mohsin, Yanxia Luo, Lili Xie, Yan Peng, Qizheng Wang, Haifeng Hang, Yingping Zhuang, Meijin Guo
Format: Article
Language:English
Published: BMC 2019-03-01
Series:Stem Cell Research & Therapy
Subjects:
Embryonic stem cells
Embryonic Sertoli cells
Lentiviral transduction
Molecular mechanism
Gonadogenesis
Male determinant factors
Online Access:http://link.springer.com/article/10.1186/s13287-019-1180-6

Internet

http://link.springer.com/article/10.1186/s13287-019-1180-6

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