Revealing the mechanism of lymphoid and myeloid cell differentiation and transdifferentiation through landscape quantification
The hematopoietic stem cells (HSCs) can differentiate to myeloid and lymphoid lineages, which lead to more specific differentiated cells. This cell fate decision process is governed by an underlying gene regulatory network. However, its underlying mechanism remains to be fully clarified. In this wor...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
American Physical Society
2021-02-01
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| Series: | Physical Review Research |
| Online Access: | http://doi.org/10.1103/PhysRevResearch.3.013186 |