Flanking heterozygosity influences the relative probability of different base substitutions in humans

Understanding when, where and which mutations are mostly likely to occur impacts many areas of evolutionary biology, from genetic diseases to phylogenetic reconstruction. Africans and non-African humans differ in the mutability of different triplet base combinations. Africans and non-Africans also d...

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Bibliographic Details
Main Author: William Amos
Format: Article
Language:English
Published: The Royal Society 2019-09-01
Series:Royal Society Open Science
Subjects:
Online Access:https://royalsocietypublishing.org/doi/pdf/10.1098/rsos.191018