STIM1/SOX2 proteins are co-expressed in the tumor and microenvironmental stromal cells of pancreatic ductal adenocarcinoma and ampullary carcinoma

STIM1/SOX2 proteins are co-expressed in the tumor and microenvironmental stromal cells of pancreatic ductal adenocarcinoma and ampullary carcinoma

Abstract Pancreatic ductal adenocarcinoma (PDAC) and ampullary carcinoma (AAC) are lethal malignancies with modest benefits from surgery. SOX2 and STIM1 have been linked to anticancer activity in several human malignancies. This study included 94 tumor cases: 48 primary PDAC, 25 metastatic PDAC, and...

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Bibliographic Details
Main Authors: Dina Sweed, Sara Mohamed Abd Elhamed, Hayam Abdel Samie Aiad, Nermine Ahmed Ehsan, Aiat Shaban Hemida, Marwa Mohammed Dawoud
Format: Article
Language:English
Published: BMC 2024-03-01
Series:World Journal of Surgical Oncology
Subjects:
Ampullary carcinoma
BCL2
Immunohistochemistry
Pancreatic ductal adenocarcinoma
SOX2
STIM1
Online Access:https://doi.org/10.1186/s12957-024-03356-y

Internet

https://doi.org/10.1186/s12957-024-03356-y

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