Integrated approaches for the recognition of small molecule inhibitors for Toll-like receptor 4
Toll-like receptors (TLRs) are pattern recognition receptors present on the surface of cells playing a crucial role in innate immunity. One of the TLRs, TLR4, recognizes LPS (Lipopolysaccharide) as its ligand leading to the release of anti-inflammatory mediators as well as pro-inflammatory cytokines...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2023-01-01
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Series: | Computational and Structural Biotechnology Journal |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2001037023002556 |