Effect of PD-L1 expression on the efficacy of pemetrexed-based chemotherapy in patients with advanced lung adenocarcinoma and its mechanism

Background and purpose: The expression of programmed death ligand-1 (PD-L1) in lung cancer not only is the most important biomarker for predicting the efficacy of programmed death-1 (PD-1)/PD-L1 inhibitors, but also may affect the efficacy of epidermal growth factor receptor-tyrosine kinase inhibito...

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Bibliographic Details
Main Author: SHI Maolin , BAI Yudi , WANG Chao , LI Siqi , ZHOU Daijun , PENG Jingjing , SUN Feifan , LI Dong , ZHANG Tao
Format: Article
Language:English
Published: Editorial Office of China Oncology 2021-04-01
Series:Zhongguo aizheng zazhi
Subjects:
Online Access:http://www.china-oncology.com/fileup/1007-3639/PDF/20210410.pdf