Expression of p130cas, E-cadherin and β-catenin and their correlation with clinicopathological parameters in non-small cell lung cancer: p130cas over-expression predicts poor prognosis

p130cas (p130 Crk-associated substrate) is a scaffolding protein and plays an important role in regulating focal adhesion and driving cell migration. Also, the destruction of E-cadherin/β-catenin adhesive complex is one of the changes that characterizes the invasive phenotype of tumors<strong...

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Bibliographic Details
Main Authors: Yuan Miao, Ai-Lin Li, Liang Wang, Chui-Feng Fan, Xiu-Peng Zhang, Hong-Tao Xu, Yang Han, Yang Liu, Enhua Wang
Format: Article
Language:English
Published: Via Medica 2012-10-01
Series:Folia Histochemica et Cytobiologica
Subjects:
Online Access:http://czasopisma.viamedica.pl/fhc/article/view/11957