Expression of p130cas, E-cadherin and β-catenin and their correlation with clinicopathological parameters in non-small cell lung cancer: p130cas over-expression predicts poor prognosis
p130cas (p130 Crk-associated substrate) is a scaffolding protein and plays an important role in regulating focal adhesion and driving cell migration. Also, the destruction of E-cadherin/β-catenin adhesive complex is one of the changes that characterizes the invasive phenotype of tumors<strong...
Main Authors: | , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Via Medica
2012-10-01
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Series: | Folia Histochemica et Cytobiologica |
Subjects: | |
Online Access: | http://czasopisma.viamedica.pl/fhc/article/view/11957 |