Influence of pH modifiers on the dissolution and stability of hydrochlorothiazide in the bi- and three-layer tablets

During the past few years, the studies of bi- and multi-layered tablets increased due to the consumption of several different drugs per day by a patient and requests for appropriate patient compliance. The demographic shift toward older population increases the use of combination therapy as polyphar...

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Bibliographic Details
Main Authors: Blatnik Sandra Urek, Dreu Rok, Srčič Stanko
Format: Article
Language:English
Published: Sciendo 2015-12-01
Series:Acta Pharmaceutica
Subjects:
Online Access:https://doi.org/10.1515/acph-2015-0031