Ethanol-Mediated Stress Promotes Autophagic Survival and Aggressiveness of Colon Cancer Cells via Activation of Nrf2/HO-1 Pathway

Ethanol-Mediated Stress Promotes Autophagic Survival and Aggressiveness of Colon Cancer Cells via Activation of Nrf2/HO-1 Pathway

Epidemiological studies suggest that chronic alcohol consumption is a lifestyle risk factor strongly associated with colorectal cancer development and progression. The aim of the present study was to examine the effect of ethanol (EtOH) on survival and progression of three different colon cancer cel...

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Bibliographic Details
Main Authors: Cesare Cernigliaro, Antonella D’Anneo, Daniela Carlisi, Michela Giuliano, Antonella Marino Gammazza, Rosario Barone, Lucia Longhitano, Francesco Cappello, Sonia Emanuele, Alfio Distefano, Claudia Campanella, Giuseppe Calvaruso, Marianna Lauricella
Format: Article
Language:English
Published: MDPI AG 2019-04-01
Series:Cancers
Subjects:
colon cancer cells
ethanol
Nrf2
HO-1
ER stress
autophagy
MMPs
Online Access:https://www.mdpi.com/2072-6694/11/4/505

Internet

https://www.mdpi.com/2072-6694/11/4/505

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