SMOC-1 interacts with both BMP and glypican to regulate BMP signaling in C. elegans.

Secreted modular calcium-binding proteins (SMOCs) are conserved matricellular proteins found in organisms from Caenorhabditis elegans to humans. SMOC homologs characteristically contain 1 or 2 extracellular calcium-binding (EC) domain(s) and 1 or 2 thyroglobulin type-1 (TY) domain(s). SMOC proteins...

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Bibliographic Details
Main Authors: Melisa S DeGroot, Byron Williams, Timothy Y Chang, Maria L Maas Gamboa, Isabel M Larus, Garam Hong, J Christopher Fromme, Jun Liu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-08-01
Series:PLoS Biology
Online Access:https://doi.org/10.1371/journal.pbio.3002272