In-silico study of antisense oligonucleotide antibiotics

Background The rapid emergence of antibiotic-resistant bacteria directly contributes to a wave of untreatable infections. The lack of new drug development is an important driver of this crisis. Most antibiotics today are small molecules that block vital processes in bacteria. To optimize such effect...

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Bibliographic Details
Main Authors: Erica S. Chen, Eric S. Ho
Format: Article
Language:English
Published: PeerJ Inc. 2023-11-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/16343.pdf