In-silico study of antisense oligonucleotide antibiotics
Background The rapid emergence of antibiotic-resistant bacteria directly contributes to a wave of untreatable infections. The lack of new drug development is an important driver of this crisis. Most antibiotics today are small molecules that block vital processes in bacteria. To optimize such effect...
Main Authors: | Erica S. Chen, Eric S. Ho |
---|---|
Format: | Article |
Language: | English |
Published: |
PeerJ Inc.
2023-11-01
|
Series: | PeerJ |
Subjects: | |
Online Access: | https://peerj.com/articles/16343.pdf |
Similar Items
-
Silencing Antibiotic Resistance with Antisense Oligonucleotides
by: Saumya Jani, et al.
Published: (2021-04-01) -
Quantitative fluorescence imaging of antisense oligonucleotide mediated knockdown
by: Chan, Nicholas Zhen Woon
Published: (2024) -
History of Research on Antisense Oligonucleotide Analogs
by: Jack S. Cohen
Published: (2021-03-01) -
Transport Oligonucleotides—A Novel System for Intracellular Delivery of Antisense Therapeutics
by: Oleg V. Markov, et al.
Published: (2020-08-01) -
The Use of Antisense Oligonucleotides in Evaluating Survivin as a Therapeutic Target for Radiation Sensitization in Lung Cancer
by: Shinohara Eric T., et al.
Published: (2004-01-01)