Neoantigen cancer vaccine augments anti-CTLA-4 efficacy
Abstract Immune checkpoint inhibitors (ICI) based on anti-CTLA-4 (αCTLA-4) and anti-PD1 (αPD1) are being tested in combination with different therapeutic approaches including other immunotherapies such as neoantigen cancer vaccines (NCV). Here we explored, in two cancer murine models, different ther...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2022-02-01
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Series: | npj Vaccines |
Online Access: | https://doi.org/10.1038/s41541-022-00433-9 |