Serum concentrations of substance P in cholestasis
Substance P (SP) is an excitatory neuropeptide that acts via the neurokinin-I receptor (NK-1) in the nervous system. Pruritus, a complication of cholestasis, is a nociceptive stimulus; thus, we hypothesized that cholestasis would be associated with increased neurotransmission via SP as evidenced, in...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2010-04-01
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Series: | Annals of Hepatology |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1665268119316588 |