Methods for discovering genomic loci exhibiting complex patterns of differential methylation
Abstract Background Cytosine methylation is widespread in most eukaryotic genomes and is known to play a substantial role in various regulatory pathways. Unmethylated cytosines may be converted to uracil through the addition of sodium bisulphite, allowing genome-wide quantification of cytosine methy...
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| Format: | Article |
| Language: | English |
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BMC
2017-09-01
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| Series: | BMC Bioinformatics |
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| Online Access: | http://link.springer.com/article/10.1186/s12859-017-1836-0 |