Continuous Low-Dose (Metronomic) Chemotherapy on Rat Prostate Tumors Evaluated Using MRI In Vivo and Comparison with Histology

Continuous Low-Dose (Metronomic) Chemotherapy on Rat Prostate Tumors Evaluated Using MRI In Vivo and Comparison with Histology

Continuous low-dose (metronomic) therapy, based on cyclophosphamide (CTX) combined with thalidomide (Tha), was evaluated on Dunning prostate R3327-AT1 rat tumors. Significantly delayed tumor growth (P < .001) was observed with oral CTX alone at a low dose (metronomic cyclophosphamide or M-CTX; 30...

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Bibliographic Details
Main Authors: Dawen Zhao, Lan Jiang, Eric W. Hahn, Ralph P. Mason
Format: Article
Language:English
Published: Elsevier 2005-07-01
Series:Neoplasia: An International Journal for Oncology Research
Subjects:
continuous low-dose (metronomic) chemotherapy
prostate tumor
magnetic resonance imaging (MRI)
immunohistochemistry
antiangiogenesis
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558605800892

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http://www.sciencedirect.com/science/article/pii/S1476558605800892

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