CD161 expression defines new human γδ T cell subsets

CD161 expression defines new human γδ T cell subsets

Abstract γδ T cells are a highly versatile immune lineage involved in host defense and homeostasis, but questions remain around their heterogeneity, precise function and role during health and disease. We used multi−parametric flow cytometry, dimensionality reduction, unsupervised clustering, and se...

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Bibliographic Details
Main Authors: Amali Karunathilaka, Samuel Halstrom, Patricia Price, Michael Holt, Viviana P. Lutzky, Denise L. Doolan, Andreas Kupz, Scott C. Bell, Rachel M. Thomson, John J. Miles, Champa N. Ratnatunga
Format: Article
Language:English
Published: BMC 2022-02-01
Series:Immunity & Ageing
Subjects:
Cellular immunity
CD161
γδ T cell
γδ T cell subsets
γδ T cell multifunctionality
High dimensional flow cytometry
Online Access:https://doi.org/10.1186/s12979-022-00269-w

Internet

https://doi.org/10.1186/s12979-022-00269-w

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