Dimming the Powerhouse: Mitochondrial Dysfunction in the Liver and Skeletal Muscle of Intrauterine Growth Restricted Fetuses

Dimming the Powerhouse: Mitochondrial Dysfunction in the Liver and Skeletal Muscle of Intrauterine Growth Restricted Fetuses

Intrauterine growth restriction (IUGR) of the fetus, resulting from placental insufficiency (PI), is characterized by low fetal oxygen and nutrient concentrations that stunt growth rates of metabolic organs. Numerous animal models of IUGR recapitulate pathophysiological conditions found in human fet...

Full description

Bibliographic Details
Main Authors: Alexander L. Pendleton, Stephanie R. Wesolowski, Timothy R. H. Regnault, Ronald M. Lynch, Sean W. Limesand
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Endocrinology
Subjects:
mitochondrial metabolism
tricarboxylic acid (TCA) cycle
intrauterine growth restriction (IUGR)
placental insufficiency
oxidative phosphorylation
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2021.612888/full

Internet

https://www.frontiersin.org/articles/10.3389/fendo.2021.612888/full

Similar Items